Abstract
Context: 1 Lymph nodes are one of the most frequently sampled tissues and lymphadenopathy are rst evaluated by ne needle aspiration cytology . Lymphadenopathy is one of the commonest presentations in surgical department with varied etiology ranging from Reactive, Inammatory condition to malignancy. Aims: The aim of present study was to evaluate the correlation between the cytological and histopathological diagnosis of lymph node FNAC and Biopsies and to evaluate the sensitivity, specicity and predictive value of FNAC of lymph nodes diagnosed as tuberculosis and metastatic carcinoma. Settings and Design: The study is done in SMMCHRI for a period of one year which included a total of 174 patients referred from surgical department who underwent FNAC of lymph nodes, out of which 89 patients had lymph node biopsies for histopathological evaluation. Methods and Material: Aspiration smears and histopathological slides were evaluated and results were calculated for sensitivity, specicity and predictive value of FNAC and henceforth Cytological and Histopathological correlation is studied. Statistical analysis used: Sensitivity, Specicity, Predictive value and Diagnostic accuracy are calculated Results: Reactive lymphadenitis was seen in 35 patients followed by tubercular granulomatous lymphadenitis in 26 patients and malignant lesions in 28 patients. Correlating the ndings, we could achieve 100% sensitivity and 96.9% specicity for tubercular lymphadenopathy and 100% and 98.6% for metastatic deposits respectively. Conclusions: We have found FNAC as a satisfactory tool in diagnosis of tubercular and malignant lymphadenopathy. FNAC when used in conjunction with clinical, radiological and laboratory investigations can be a cost-effective method for the diagnosis of lymphadenopathy
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