Abstract
Publisher Summary This chapter discusses the cytokinesis in fission yeast Schizosaccharomyces pombe. The process of cytokinesis in animal cells has been the subject of a large number of ingenious embryological experiments. While these experiments have revealed a great deal at a mechanistic level about what factors influence cleavage furrow formation, much less is known at a molecular level. Because much of the current understanding of the eukaryotic cell cycle at a molecular level is derived from genetic studies in the two yeasts, Saccharomyces cerevisiae and Schizosaccharomyces pombe, it seems likely that the study of cytokinesis in yeast will also be revealing. Schizosaccharomyces pombe is particularly well suited for the study of cytokinesis, because like higher eukaryotes, S. pombe divides by medial fission through the use of an F-actin contractile ring. The actin cytoskeleton in fission yeast contains three major types of actin structures.
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