Abstract
Publisher Summary This chapter explains how cytokines control brain development. The role of cytokines in lineage commitment and cell survival is somewhat analogous to the role of hematopoietins in blood cell development. The chapter outlines the significant developmental signposts that are involved in the progressive sculpting of the central and peripheral nervous systems, following neurulation and dorsoventral patterning of the neural tube and will discuss the cytokines associated with each of these stages of development. It then describes the specific roles of individual cytokines in mediating discrete cellular events during neurogenesis and the developmental profiles of expression of the relevant ligands and receptor subunits. The interrelationships between progressive developmental events and their modulation by subclasses of epigenetic signals will then be placed within a specific biological context to allow predictions to be made concerning the likely future course of cytokine research in developmental neurobiology.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
