Abstract

Background Cytokines have been shown to be important signal molecules in the development of allergy and asthma, especially the regulatory cytokine IL-10, which has been shown to correlate with higher risk of allergy development in children [1]. Research results regarding cytokine levels in umbilical cord blood plasma vary greatly; some studies find the concentration of cytokines detectable whereas other studies do not. The purpose of this pilot study was to determine if cytokines could be measured from cord blood plasma using IL-10 ELISAs and xMAP Luminex assay.

Highlights

  • Cytokines have been shown to be important signal molecules in the development of allergy and asthma, especially the regulatory cytokine IL-10, which has been shown to correlate with higher risk of allergy development in children [1]

  • The IL-10 ELISA showed that IL-10 was present in 1 of 6 the plasma samples examined

  • Using the Milliplex assay, IL-1b was detectable in 60% of the samples; IL-2 in 50% of the samples; IL-4 and IL-5 in 90% of the samples; IL-6, IL-7 and IL-8 in 100% of the samples; IL-10 in 90% of the samples; IL-12(p70) in 80% of the samples; IL-13 in 100%

Read more

Summary

Background

Cytokines have been shown to be important signal molecules in the development of allergy and asthma, especially the regulatory cytokine IL-10, which has been shown to correlate with higher risk of allergy development in children [1]. Research results regarding cytokine levels in umbilical cord blood plasma vary greatly; some studies find the concentration of cytokines detectable whereas other studies do not. The purpose of this pilot study was to determine if cytokines could be measured from cord blood plasma using IL-10 ELISAs and xMAP Luminex assay

Methods
Results
Conclusions
Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.