Abstract

Cytokine control of interstitial collagenase and collagenase-3 gene expression in human chondrocytes

Highlights

  • Acknowledgments—We thank Dr David Woolley for providing the primary cells, Dr Peter Angel for the unpublished sequence of the mouse collagenase AP-1 site, Dr Carlos Lopez-Otin for the unpublished sequence of the human collagenase-3 AP-1 site and for the human collagenase-3 probe, and Dr Hal Van Wart for his support

  • The single base change made in the mutant stromelysin AP-1 site is indicated by an asterisk

  • Sequences are derived from the following sources: collagenase-1 AP-1 (15), collagenase-3 AP-1

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Summary

Introduction

Acknowledgments—We thank Dr David Woolley for providing the primary cells, Dr Peter Angel for the unpublished sequence of the mouse collagenase AP-1 site, Dr Carlos Lopez-Otin for the unpublished sequence of the human collagenase-3 AP-1 site and for the human collagenase-3 probe, and Dr Hal Van Wart for his support. Cytokine control of interstitial collagenase and ADP-ribosylation of the G protein Rho inhibits collagenase-3 gene expression in human chondrocytes. Page 23579, Fig. 3 legend should read: FIG.

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