CYTOHISTOLOGICAL SPECTRUM OF BREAST LESIONS WITH RESPECT TO THE IAC YOKOHAMA SYSTEM FOR REPORTING BREAST FINE ASPIRATION CYTOLOGY-A TWO YEAR TERTIARY CARE CENTER EXPERIENCE

Abstract

ntroduction: The new International Academy of Cytology (IAC) Yokohama System for Reporting Breast FNABC, supported by IAC and developed by an International “Breast Group”, was proposed to establish a comprehensive structured approach so as to standardize the diagnostic approach and improve reproducibility. To categorize the breast FNAB samples ac Aim: cording to this new system of Reporting and to assess various statistical parameters including Risk of Malignancy. Breast FNAB Materials And Method: specimens obtained in the cytology section of the Department of Pathology, AMCH were reported using the newly proposed IAC Yokohama System. The statistical parameters were calculated taking Histopathology as the Gold Standard. A total of 280 Cases with breast l Results And Observation esions were included, of which 16 of the Cases were categorized as Inadequate, 152 as benign, 5 as atypical, 16 as suspicious for malignancy and 91 as malignant. The ROM for each category was obtained. Considering Malignant and Suspicious for Malignancy cases as true positives, the Sensitivity was 95.05%, Specicity 98.46%, PPV 97.96%, NPV 96.24% and Diagnostic Accuracy 96.97%. The IAC Yokohama system for Reportin Conclusion g Breast FNAB cytology effectively straties breast lesions thus providing guidance to both cytopathologists and clinicians leading to better patient care