Cytogenetic study of Stomach cancer in Erbil City

Abstract

Stomach cancer is the fourth most common type of cancer cancer and the second leading cause of cancer- related death through the world. The objective of the present study is to know the chromosomal aberrations in peripheral blood of stomach cancer patients. The present study was carried out on 50 patients who were suffering from stomach cancer in Erbil city and 25 healthy individuals as a control group in both sex and different age groups. Blood samples were collected and chromosomal study was performed. Because stomach cancer is a heterogeneous disorder; genetic factors, smoking habit, alcohol habit, Helicobacter pylori ( H .pylori) bacterial infection and various environmental factors contribute to its development. Other factors was also studied included patient gender , age and blood groups. The results of the present study suggest that highest value of chromosomal aberrations was (Dicentric chromosome) which occurred in males at fifth age group (65-74) ,also shown that most patients are males at age group(45-64), most of them have smoking and alcohol habit with Helicobacter pylori( H .pylori) bacterial infection and most patients are A blood type .