Abstract
The digestive gland of Cryptochiton stelleri was shown to contain cytochrome P-450, benzo[ a]pyrene hydroxylase (BPH), and NAPHH-cytochrome P-450 reductase. Glutathione- S-transferase, UDP-glucuronosyltransferase, and UDP-glucosyltransferase activities also were observed. After treating chitons three weeks with a cytochrome P-450 inducer, β-naphthoflavone (BNF), a significant ( P < 0.05) increase in BPH was found in treated animals. The major metabolites extracted after incubation of BP with chiton digestive gland microsomes were quinones. However, a quantitative difference in quinone production was seen between controls (72.7%) and BNF-treated animals (42.9%). Neither ethoxycoumarin- O-deethylase (ECOD) or ethoxyresorufin- O-deethylase (EROD) was detected in controls or BNF-treated animals.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
