Abstract

The experiments reported below were designed to test the notion that viral inclusion bodies represent virus colonies and that the inclusion bodies undergo a phase of rapid increase of virus material (and of the enzymatic activities with which it may be associated) followed by a phase of decline. The work was based on the assumption that virus particles of most animal virus diseases contain DNP (desoxyribonucleoproteins). Herpetic inclusion bodies, in different stages of their development, have accordingly been examined by cytochemical methods for their DNP content and for selected enzymatic activities.

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