Cytobacteriological Examination Of Urines And Urinary Tract Infection Seen In The Laboratory Of University Hospital Of Befelatanana

Abstract

Background : Urinary tract infections are common in the community and the hospitals. The aims of this study are to describe the socio-demographic characteristics, uropathogen frequencies, and antimicrobial resistance rates of all patients with urinary tract infections. Methods : This is a prospective and descriptive study of 362 cytobacteriological urine examinations for a period of six months from July to December 2020. This study was carried out in the laboratory of the University Hospital Joseph Raseta Befelatanana Antananarivo in Madagascar. Results : Among 362 patients, 117 (32.3%) were affected by urinary tract infections. Women (37.1%) were more affected by men (26.3%) (p=0.02). Similarly, patients over 60 years of age (39%)(p=0.04) were the most affected by urinary tract infections. Bacteria were represented by enterobacteria (58.1%), streptococci (8.5%), non-fermenting gram-negative bacilli (3.4%), staphylococci (1.7%) and other microorganisms (28.2%). Concerning the antibiotic resistance, ESBL-producing Enterobacteriacea were more resistant to antibiotics than non-ESBL-producing Enterobacteriaaceae (81.8% versus 60.9% to cotrimoxazole, 72.7% versus 19.6% to ciprofloxacin, 59.1% versus 6.5% to gentamycin and 18.2% versus 10.9% to chloramphenicol). All isolates of non-fermenting gram-negative bacilli were resistant to ticarcillin and gentamycin, 8 (80%) isolates of streptococci to lincomycin and an isolate of staphylococci to penicillin G and tetracycline. Conclusion : Bacteriological examination of urines and antibiogram were very important to improve the management of patients with urinary tract infections.