Cytoarchitecture and responsiveness of the medial ansate region of the cat primary somatosensory cortex.

Abstract

To understand its relationship to somatosensory areas in other species, we studied the rostral bank of the medial ansate sulcus in adult cats. Neurons in the shoulder and upper part of the sulcal wall responded to low-threshold cutaneous stimuli much like neurons on the crown of the gyrus, whereas neurons in some deeper portions of the sulcus required more intense but innocuous somatic stimuli. Because we found much of the body surface re-represented in this area, we suggest that, besides the representation in area 3b, there is another cutaneous representation of the hindlimb and trunk located on the gyral crown near the medial end of the medial ansate sulcus and of the forelimb and trunk within the medial ansate sulcus. Posterior to this second cutaneous representation, many parts of the body were also represented in regions activated by more intense stimuli and having a different cytoarchitecture, suggesting that they were part of another body representation. Area 3b and the shoulder of the gyrus were distinguished by relatively intense acetylcholinesterase staining of layers III and IV. In the wall of the sulcus, all layers except layer I were uniformly stained to a point where electrophysiological recordings showed the cortex to be unresponsive, whereupon the outer two-thirds of layer I became very pale. Neurons activated by afferents from knee joints were found only in a small area; we did not find a mediolateral band serving joint afferents as is reported in primates. These data suggest that cat somatosensory cortex differs in some ways from primates but that it contains multiple representations of the body, as do most other mammals.