Abstract
A case of cystic foreign body giant cell granuloma is presented. The patient, nineteen years of age, known case of Xeroderma Pigmentosum, presented to the maxillofacial unite, Basrah General Hospital, Iraq, with slowly enlarging cervical cystic mass. Examination revealed cystic swelling in the mid-left side of the neck of six months duration. The mass was not tender and was immobile. Aspiration revealed straw colored fluid. The excised mass, showed cystic lesion, the base of which had an extensive soft tissue growth, histologically consisted of foreign body giant cell granulomas. There was no recurrence at a follow-up of 17 years.
Highlights
Xeroderma Pigmentosum is a rare hereditary disease transmitted as an autosomal recessive disorder, characterized by extreme sensitivity to sunlight1
The Granulomatous reaction occurring simultaneously with metastatic squamous cell carcinoma in cervical lymph nodes draining laryngeal carcinoma has been described by Ophir et al5, upon finding of epithelioid granuloma in cervical lymph node, a malignant tumor of head and neck should be considered differential diagnosis possibility
The data presented by Homa et al2, suggests that radiation injury in squamous cell carcinoma may be manifested by marked hyperkeratinization of tumor cells, keratin compounds liberated induce sever foreign body giant cell reaction
Summary
Xeroderma Pigmentosum is a rare hereditary disease transmitted as an autosomal recessive disorder, characterized by extreme sensitivity to sunlight1. The operations were to excise six squamous cell carcinomas involving the anterior part of the tongue, the vermilion border of the lower lip, commeasure of the mouth, skin of the face and the scalp; these were presented as erosive or, ulcerative lesions and exophytic lobulated partly infiltrative masses (fig.1).
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