Abstract
The mucopolysaccharide content of skin fibroblast cultures from patients and heterozygous carriers of cystic fibrosis was increased as compared to that from normal, non-carrier individuals. The distribution of mucopolysaccharides in these cultures (with the intracellular uronic acid similar to control cells and that in the extracellular matrix and medium increased) was markedly different from that seen in cultures derived from normals and patients with Hurler's syndrome.
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