Abstract
Cystic fibrosis (CF) is a chronic genetic disease with social significant weight because it influences on social humanitarian part of health and on sources of health care system as well. Materials and methods. Data of CF Register and treatment methodology based on clinical guidelines were used for analysis. Direct and indirect medical costs as well as indirect costs have been calculated per one patient per year. Direct costs included diagnostic costs and treatment based on Obligatory medical Insurance fund tariffs, costs of drugs and medical devices, rehabilitation, payments due to disability; indirect costs included loss of GDP. Results. Total expenditures were calculated as 3,1 mln RUR for one patient annually, direct medical costs were 71 % of total. Main part of expenditures was allocated for out-patient stage of treatment — 1,57 mln RUR. Exacerbations costs were estimated as 399,4 thousand RUR. Indirect medical cost was 314,6 thousand RUR, and indirect cost as 582,9 thousand RUR as well annually. Total economic burden of CF for Russian Federation was calculated as 10,37 bln RUR/year, main part was a direct medical expenditures — 73 %. Conclusion. CF is a big social-economic burden in the Russian conditions. Reducing the number of exacerbations and improving lung function, as well as increasing the life expectancy of patients with CF due to introduction of new technologies in health care (targeted therapy) is aimed at reducing the social burden of the disease, which will require increasing the availability of effective (targeted) drugs in the future.
Highlights
Cystic fibrosis (CF) is a chronic genetic disease with social significant weight because it influences on social humanitarian part of health and on sources of health care system as well
Data of CF Register and treatment methodology based on clinical guidelines were used for analysis
Total economic burden of CF for Russian Federation was calculated as 10,37 bln RUR/year, main part was a direct medical expenditures — 73 %
Summary
При расчёте популяции пациентов учтено, что в 2018 году Российский регистр пациентов с МВ содержал информацию о 3 142 пациентах, из них 958 в возрасте старше 18 лет (24,7 %) [2]. При оценке затрат учтены данные Регистра пациентов с МВ, который ведётся с 2011 г. И содержит информацию о численном и возрастном составе пациентов, охвате диагностическими и лечебными процедурами, а также исходах в связи с заболеванием [2]. При оценке связанных с заболеванием затрат учтены клинические рекомендации по лечению пациентов с кистозным фиброзом (муковисцидозом) (2020 г.) [1]. Базовая ставка при оказании медицинской помощи в условиях круглосуточного стационара в 2020 году составляет 28 850,94 руб., в условиях дневного стационара — 11 944,87 руб. При расчёте затрат на скрининг учтено количество новорождённых [20]. Санкт-Петербург [21] (табл. 1)
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