Abstract
A method was developed for determination of gold in body fluids and tissues using electrothermal atomic absorption spectrophotometry with Zeeman effect background correction. There was excellent recovery of gold added to undiluted blood plasma. However, there was generally poor recovery of gold added to the intraocular fluids and tissue digests. Addition of plasma proteins and amino acids as matrix modifiers increased both the absorbance signal of the standard and the recovery of gold added to intraocular fluids and tissue digests. Cysteine (20 mg ml ) was found to be the most effective matrix modifier in all cases. This signal increasing effect may be limited to gold since neither protein nor amino acids were effective in increasing absorbance signals of other elements, including Fe, Pb and Cu.
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