Abstract
肝肾综合征(HRS)是终末期肝病(MELD)的严重并发症,临床常分为Ⅰ型HRS:其特征为快速进行性肾功能损害2周内血清肌酐(Scr)较基线升高2倍以上并＞221μmol/L;Ⅱ型HRS:特征为稳定或非进行性肾功能损害,Scr在133 ～ 221 μmol/L之间,或血清肌酐清除率(Ccr)＜40％[1].引起HRS的机制主要是肾动脉显著收缩及体循环舒张调节功能紊乱,从而导致动脉血压降低,肾动脉灌注严重不足,肾小球滤过率(GFR)明显降低所致.肝肾综合征为功能性肾脏损害,因此早期预防、诊断及积极合理治疗有可能逆转肾功能衰竭(AKI)[2].本研究对肝肾综合征患者采用动态监测血清胱抑素C(cystian C,CyC)及肾动脉血流阻力指数(RI)在肝肾综合征的早期诊断及治疗上取得了一定的临床价值及经验,现总结如下. 关键词：肝肾综合征;肝硬化;血清胱抑素C;肾动脉血流阻力指数
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