Abstract
Copper sulfate (CuSO4) was used to reduce the toxic effect of nano zinc oxide (nZnO) in carp (Cyprinus carpio L.). Copper sulfate (0.3 mg/L) was used for 1 hour in carp fish exposed to n ZnO in sub-lethal concentration (9 mg/L) for seven days. Also for comparison second group were only exposed to n ZnO in sub-lethal concentration (9 mg/L) for seven days. There were significant changes in concentration of Metallothionein (MT) and some biochemical parameters in serum of fish blood in all groups compared with non-treated groups. CuSO4 has play a major role in reducing the toxicity of n ZnO in some blood serum parameters.
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