Abstract
Cyperus rotundus is a folk medicine with many benefits such as anti-inflammatory, anti-cancer, antioxidant, etc. It is widely used in many parts of the world. This study provided data on the phytochemical composition of Cyperus rotundus rhizome, including the active groups of alkaloids, flavonoids, phenols, tannins, and triterpenoids. The polyphenols content in the ethanolic and aqueous extracts of Cyperus rotundus were 26.89 ± 4.33 (mgGAE/g) and 51.84 ± 6.46 (mgGAE/g), respectively. While, the flavonoids content in the ethanolic and aqueous extracts of Cyperus rotundus were 78.03 ± 3.11 (mgQE/g) and 20.28 ± 2.25 (mgQE/g), respectively. According to the ABTS assay, the IC50 values of the aqueous and ethanolic extracts were 117.8 ± 19.85 (μg/ml) and 162.02 ± 11.43 (μg/ml), respectively. According to the DPPH assay, the IC50 values of Cyperus rotundus extracted by water and alcohol were 337.42 ± 22.84 (μg/ml) and 447.53 ± 33.8 (μg/ml), respectively. With the rich presence of secondary compounds, antioxidant activity confirmed in many studies, Cyperus rotundus is evaluated as having potential applications in many different fields such as pharmaceuticals, cosmetics, and functional foods.
Highlights
Nowadays, herbs and natural active ingredients are more and more popular due to their availability and minimal side effects
Cyperus rotundus is a medicinal herb used in folk medicine in many countries such as India, Iran, China, Japan, Vietnam, etc. [3, 4]
Following the methods of Aug et al [10] and Nguyen et al [11], the chemical composition of Cyperus rotundus was determined by observing specific reactions performed in vitro
Summary
Herbs and natural active ingredients are more and more popular due to their availability and minimal side effects. Cyperus rotundus is a medicinal herb used in folk medicine in many countries such as India, Iran, China, Japan, Vietnam, etc. The results of phytochemical analysis showed that the leaves and rhizomes of Cyperus rotundus contain a variety of compounds with high biological activity such as glycosides, tannins, reducing sugars, alkaloids, flavonoids, polyphenols, terpenoids, saponins, and phlorotannin. Many groups of compounds present in this plant have good biological activity, such as polyphenols, flavonoids, and tannins [6]
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