Abstract
Epidemiologic studies have evaluated the association between 3801T>C polymorphism of the CYP1A1 gene and risk for idiopathic male infertility [1]. The CYP1A1 polymorphism can alter the level of gene expression and messenger RNA stability of enzymes which play a crucial role in metabolism of compounds that have a potential reproductive toxicity in the male reproductive tract. However, there have been no studies which have evaluated the 3801T>C polymorphism and its relationship to semen analysis (SA) parameters and fertilization rates in male patients undergoing IVF/ICSI.
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