Cyclometallated platinum compounds with chiral imines. Crystal structure of [PtMe(2-FC6H3CHN-(S)-CHMePh)(PPh3)

Abstract

The reactions of [Pt2Me4(μ-SMe2)2] (1) with ligands ArCHN-(S)-CHMePh (Ar2-BrC6H4 (2a), 2,6-Cl2C6H3 (2b), C6F5 (2c), 2-FC6H4 (2d), 2-CF3C6H4 (2e)), give either cyclometallated compounds [PtMe2X(RCHN-(S)-CHMePh)(SMe2)] (3), by intramolecular activation of C–X (X=Br, Cl or F) bonds, or compounds [PtMe(RCHN-(S)-CHMePh)(SMe2)] (5), by orthometallation, followed by methane elimination. The reactions of these compounds with PPh3 result in the formation of [PtMe2X(RCHN-(S)-CHMePh)(PPh3)] (4), or [PtMe(RCHN-(S)-CHMePh)(PPh3)] (6), respectively. Oxidative addition of methyl iodide to compounds 6 produces the corresponding complexes 4. The NMR spectra of compounds 3 and 4 indicate that these are formed as two diastereomers. The X-ray structure of [PtMe(2-FC6H3CHN-(S)-CHMePh)(PPh3)] (6d) is reported.