Cyclic voltammetry in electrochemical oxidation of amoxicillin with Co(III) as mediator in acidic medium using Pt, Pt/Co and Pt/Co(OH)2electrodes

H Herlina,Muhammad Ali Zulfikar,B Buchari

doi:10.1051/matecconf/201819705004

H Herlina, Muhammad Ali Zulfikar + Show 1 more

Open Access

https://doi.org/10.1051/matecconf/201819705004

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Abstract

Amoxicillin is one of penicillin antibiotic groups with active β-lactam which the presence in surface water and wastes not only affects water quality but also causes long-term adverse effects on ecosystems and human health due to their resistance to natural biodegradation. The processing of organic waste electrochemically has the advantages of cheap and efficient cost, waste gas that does not contain toxic and hazardous materials. Have been studied the process of amoxicillin electro-oxidation mediated by a cobalt (III) in a cyclic voltammetry study using a platinum, Pt/Co(OH)2and Pt/Co as working electrodes in acidic medium HNO3and H2SO4as supporting electrolytes solution. The voltammogram of Pt, Pt/Co and Pt/Co(OH)2electrodes showed that higher current was found in medium of HNO30.1 M and it can be used to oxidize the amoxicillin wastes, the two anodic and cathodic peaks can be observed at potential of 200-800 mV (vs Ag/AgCl). The presence of cobalt (III) ions in the system caused the decrease of oxidation current, indicated the presence of degradation to amoxicillin.

Highlights

The most commonly antibiotics been used is the amoxicillin group, which is a type of semi-synthetic penicillin with antimicrobial properties derived from the beta-lactam ring
Some researchers have found the presence of amoxicillin in urban wastewater. [1,2,3,4] The existence of antibiotics in the environment comes from various sources such as industrial antibiotics, hospital waste and excretion from humans and livestock
ArslanAlaton et al [5] have reported that the concentration of penicillin in antibiotic waste is real in the range of 400 mg/L

Summary

Introduction

The most commonly antibiotics been used is the amoxicillin group, which is a type of semi-synthetic penicillin with antimicrobial properties derived from the beta-lactam ring. In their research Sirés and Brillas [12] have reported the electrochemical oxidation process against pharmaceutical waste from drugs such as 17β-estradiol, 17α-ethinylestradiol, diclofenac, clofibric acid, enrofloxacin, ibuprofen, ketoprofen, oxytetracycline hydrochloride, sulfamethoxazole, paracetamol and tetracycline using electrode Pt, Ti /RuO2, Ti/ SnO2, Ti/IrO2, Ti/RuO2-IrO2, and BDD [12,13,14,15,16,17]. Another electrochemical process, the mediated electrochemical oxidation (MEO), is the most promising waste treatment method for the degradation of organic compounds. AASEC 2018 advantage is that it can be performed at ambient temperature and atmospheric pressure and optimum oxidizing forces in acidic conditions. [18,19,23]

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