Abstract

The transcription factor CCAAT/enhancer-binding protein β (C/EBPβ) is a critical mediator of murine endometrial epithelial and stromal cell proliferation and differentiation. Consequently, female mice lacking the C/EBPβ gene are infertile. Previous studies have demonstrated the presence of C/EBPβ mRNA in human endometrium and upregulation of C/EBPβ during in vitro stromal decidualization. In order to further define the role of C/EBPβ in human endometrium, we characterized temporal changes in C/EBPβ mRNA abundance over the normal human menstrual cycle.

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