Abstract
AbstractFour cyclic peptides of the type cyclo (Pro‐Gly)n were synthesized and characterized. The peptides are cyclo (L‐Pro‐Gly)2, cyclo (L‐Pro‐Gly)3, cyclo (L‐Pro‐Gly)4, and cyclo (D‐Pro‐Gly‐L‐Pro‐Gly). Aspects of the cyclization reactions leading to these peptides are discussed, particularly with respect to the choice of sequence of linear precursor peptides and effects of elevated temperatures. The cyclic octapeptide, cyclo (L‐Pro‐Gly)4, was isolated as a crystalline complex with sodium thiocyanate. Experimental details of the syntheses are provided.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Paper version not known
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
