Abstract
The distribution of cyclic 3',5'-nucleotide phosphodiesterase activity in the rabbit central nervous system has been studied with a quantitative micromethod. A wide range of values between various structures was observed, but correlations with cellular density, monoamine content or other enzymes were not apparent. Phosphodiesterase activity is not uniquely associated with particular layers of the cerebral cortex or with specialized synaptic structures in the olfactory bulb. The enzyme level was unaltered in the rat superior cervical ganglion after section of preganglionic fibers, and in the cerebral cortex after lesion of the medial forebrain bundle. Major disparities in comparing these results with those of a Gomori type procedure may be explained in part by the inhibition of the enzyme by lead ion.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
