Abstract

Well, no, not yet. However, the successful development of a noninvasive neuroelectronic interface system consisting of an elementary circuit of two neurons synaptically connected to a semiconductor chip presages the advent of an era of neurocomputation and neuroengineering. The study by Zeck and Fromherz at the Max-Planck Institute in Munich shows that individual neurons from the snail Lymnaea stagnalis, immobilized onto a microelectronic substrate establish a signaling circuit connected by strong electric synapses propagating action potentials, which can be measured and controlled electronically. With further technological refining, the neuroelectronic model described in this study will probably simplify the study of synaptic modulation in neuronal networks and help unravel the underlying mechanisms of memory. Proc. Natl. Acad. Sci. U. S. A. 98, 10457–10462. SS

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