Abstract
Conventional radiotheraphy has been used for many years and its tumor control rate is hard to be raised.Accumulated dose is directly related to prognosis.According to radiobiology,the radiation dose for tumor cure is obviously higher than accumulated dose in conventional radiotheraphy.Biological effective dosage is correlated with local control rate and survival rate.Now therapeutic system of stereotactic radiation therapy can raise fractional dose to 4～8Gy.Cyberknife has obvious technical advantages in fixed mode,re-al-time position validation,image-guiding and dynamic tracing.Its fractional dose can raise to 15～30Gy,with satisfactory clinical effect.So at present,cyberknife is the best choice for high fractional dose radiation thera-py.
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