Abstract

Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by progressive cognitive decline and the memory loss. As the global population ages, the burden of AD continues to rise, highlighting the urgent need for effective treatment strategies. This abstract presents a comprehensive review of cutting edge research on drug treatment strategies and emerging therapies for AD. Recent advancements in understanding the underlying pathophysiology of AD have led to the identification of novel targets for drug development. Innovative therapeutic approaches, including disease-modifying drugs, have shown promise in preclinical and clinical studies. This thesis discusses the latest research on anti-amyloidβ (Aβ) therapies, tau-based interventions, and inflammation-targeting drugs. Additionally, emerging therapies such as immunotherapies and gene therapies, and stem cell-based treatments are explored. The thesis emphasizes the potential of calcineurin and personalized approaches in AD treatment. The integration of biomarkers and neuroimaging techniques enables early detection and intervention, facilitating more targeted and effective therapies. Furthermore, the role of lifestyle modifications, such as diet, exercise, and cognitive training, is examined in the context of AD management. This article introduces the situation of the AD and the developing trend of the research on treatment of AD. By the power of innovative drug therapies, emerging technologies and holistic approaches, there is a flush of hope of slowing disease progression, improving cognitive function, and enhancing the quality of life for individuals affected by AD.

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