Abstract
We performed Cutting Balloon angioplasty on 20 lesions in 11 heart transplant recipients 7.5 ± 3.8 years after transplantation. The mean percentage of diameter stenosis decreased from 88.3% ± 13.8% to 19.6% ± 13.7% after Cutting Balloon angioplasty without complication. Seven patients underwent follow-up angiography at 4.9 ± 1.7 months in a total of 12 lesions, and all lesions showed restenosis with a mean diameter stenosis of 84.4% ± 19.2%. Cutting Balloon angioplasty can be used to treat obstructions in cardiac transplant coronary arteries; however, it may cause exacerbation and produce a high restenosis rate.
Highlights
Journal The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 21(8)
Procedural success was achieved in all lesions with no complications during the Cutting Balloon angioplasty
Two patients underwent Cutting Balloon angioplasty as a bridge to repeat heart transplantation
Summary
Journal The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 21(8). Accelerated allograft vasculopathy significantly limits the survival of patients who undergo orthotopic heart transplantation.[1,2,3] Balloon angioplasty, directional atherectomy, and rotational atherectomy have been used to treat this disease process; these techniques have higher procedural morbidity, mortality, and restenosis compared with their use in native coronary artery atherosclerotic disease.[4,5,6,7,8] This may be because of the diffuse nature of transplant arteriopathy and its intense proliferative tissue response. The Cutting Balloon is a relatively new device for treatment of coronary artery disease.[9] The Cutting Balloon has been reported to be superior to conventional balloon angioplasty,[10] especially in treating in-stent restenosis.[11] We hypothesized that there may be advantages to using the Cutting Balloon to treat transplant arteriopathy in which diffuse disease is commonly seen
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