Cutis Verticis Gyrata in Men Affected by HIV-Related Lipodystrophy

Keshav Khanijow,Kieron S Leslie,Toby Maurer,Kathleen Mulligan,Morris Schambelan,Patrick Unemori

doi:10.1155/2013/941740

Keshav Khanijow, Kieron S Leslie + Show 4 more

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https://doi.org/10.1155/2013/941740

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Abstract

We report the occurrence of cutis verticis gyrata (CVG), a disfiguring dermatological condition, in four patients with HIV-related lipodystrophy (HIVLD). These four patients had abnormal metabolic and hormonal lab values which we compare with metabolic and hormonal perturbations cited in previous HIVLD cohorts. In addition, we describe the sole use of poly-L-lactic acid as a potential treatment for decreasing the appearance of CVG-associated ridges.

Highlights

We report the occurrence of cutis verticis gyrata (CVG), a disfiguring dermatological condition, in four patients with HIV-related lipodystrophy (HIVLD)
HIV-associated lipodystrophy (HIVLD) is a condition characterized by an atypical distribution of body fat and metabolic abnormalities including insulin resistance and dyslipidemia
Medications of particular interest that were used by some patients prior to CVG development included the thymidine nucleoside reverse transcriptase inhibitors (NRTIs) stavudine (n = 2) and zidovudine (n = 3), which are commonly associated with the adverse effect of lipodystrophy [11]

Summary

Introduction

HIV-associated lipodystrophy (HIVLD) is a condition characterized by an atypical distribution of body fat and metabolic abnormalities including insulin resistance and dyslipidemia. We report the occurrence of cutis verticis gyrata (CVG), a disfiguring dermatological condition, in four patients with HIV-related lipodystrophy (HIVLD). We describe the sole use of poly-L-lactic acid as a potential treatment for decreasing the appearance of CVG-associated ridges.

Results

Conclusion