Abstract
The occurrence of cutis verticis gyrata (CVG) was studied in an unselected series consisting of 7 patients with acromegaly (4 men and 3 women) and 5 with dystrophia myotonica (3 men and 2 women). CVG was found to occur spontaneously, or on mechanical provocation, in all the male patients but not in the females. The above 12 patients and one patient with triplo-X condition and CVG were studied from psychiatric, neurological, neurophysiological, neuroradiological, and endocrinological aspects in an attempt to find a correlate to the occurrence of CVG. A comparison between the men with CVG and the women without CVG showed no differences, however, apart from those dependent upon the sex difference in itself. CVG has been described in only a few women, all of whom have exhibited clear signs of endocrine disturbances. This circumstance, the marked male over-representation and the fact that CVG has often been found in combination with endocrine disturbances, indicates strongly that an endocrine dysfunction, possibly a disturbance of the androgen production, underlies the symptom CVG.
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