Abstract
Abstract Leishmaniasis and malignancy are emerging public health threats, manifested by a myriad of clinical presentations, and are responsible of substantial morbidity and mortality. Association of cutaneous leishmaniasis (CL) and cutaneous T cell lymphoma (CTCL) is an unusual syndrome that has rarely or even not been reported. Hereby, I report a challenging and an exceedingly rare entity of CTCL superimposed on disseminated CL (DCL) in an immunocompromised woman from Yemen. Hence, many of the questions raised in the context of parasitic carcinogenesis and the supposed potential of Leishmania parasites as oncogenes and/or risk factors for neoplastic development. Understanding this type of relationship between such skin intracellular parasites and carcinogenesis may enrich the provision of prevention, diagnosis and management of these challengeable and very hazardous diseases.
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