Cutaneous Squamous Cell Carcinoma of the Hand Presenting as Clinical Perineural Invasion

Abstract

Cutaneous squamous cell carcinoma of the hand with clinical perineural invasion is uncommon. This article describes a case of a 70-year-old female who presented with a small painful nodule on the dorsum of the left hand with minor skin surface changes who underwent excisional biopsy. A deep long subcutaneous cord was palpable extending proximally from the nodule. Intraoperative findings showed a tumour growing 2.5 cm along the dorsal cutaneous nerve of the hand, and histopathological examination revealed a primary well-differentiated squamous cell carcinoma with perineural invasion. This case highlights the importance of considering malignancy as a differential diagnosis when dealing with atypical lesions.