Cutaneous metastatic breast adenocarcinoma twenty years post-mastectomy: A lesson to learn

Abstract

Introduction: cutaneous metastasis complicating solid organ malignancy is a common clinical entity, and the primary is often metastatic breast cancer. skin metastasis from breast cancer occurs in about 25% of breast cancer patients. case report: We present a case report of a patient with a history of modified left radical mastectomy and chemotherapy for breast cancer twenty years earlier, who presented for surgical evaluation of multiple painful skin lesions. Initial punch biopsy of skin lesions reported negative for malignancy. s urgical biopsy provided tissue which demonstrated a rare histopathological morphology for cutaneous metastatic breast adenocarcinoma. conclusion: this report makes the case for considering surgical biopsy when conventional biopsy reports negative for malignancy, especially in the setting of remote or recent cancer history. It also advises prolonged relapse surveillance, well beyond the current protocol, as well as development of prognostic markers for identifying patients at risk of long disease latency after primary treatment.