Abstract
Carcinomas of the pancreas represent less than 5% of human malignant neoplasms [5], skin involvement is rare, and metastasis generally occurs at the umbilical area. There are few reported cases with cutaneous lesions disclosing a pancreatic carcinoma at sites other than the umbilical area. We report a case of cutaneous metastases of pancreatic carcinoma to the scalp. The literature on pancreatic cutaneous metastasis is reviewed and discussed.
Highlights
Histology demonstrated the dermis to be infiltrated withImmuno-histochemical staining showed a positive reaction to CK 7, CK20, CEA, Mesothelin (Figure 3), which was in keeping with well differentiated pancreatic adenocarcinoma
A 59 year old female was referred to the plastic surgical outpatients with a lesion over the scalp which was painless, bled to minor trauma and had slowly increased in size over 3 months. She had been recently diagnosed with pancreatic carcinoma of the tail with metastasis to the lung and bone following investigations for weight loss and right loin pain (Figure 1)
The provisional diagnosis made was of an ulcerated nodular Basal cell carcinoma
Summary
Immuno-histochemical staining showed a positive reaction to CK 7, CK20, CEA, Mesothelin (Figure 3), which was in keeping with well differentiated pancreatic adenocarcinoma. She had an uneventful post operative period and when followed up her scalp rotational flap had completely healed. She was readmitted with a pleural effusion and has since been receiving palliative chemotherapy with Gemiocitabine
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