Cutaneous Metastasis from Hepatocelular Carcinoma: Report of a Case

Abstract

Hepatocellular carcinoma (HCC) usually metastasizes to lung, adrenal gland, bone, and lymph nodes, while cutaneous metastasis from HCC is a rare event. Herein, we report the clinical details of a patient with cutaneous metastasis from HCC. To the best of our knowledge, this is the first case reported in the literature demonstrating that after surgical resection of HCC, isolated cutaneous metastasis becomes the first manifestation of cancer relapse, while no intra-hepatic recurrence is present. As described in other previous case reports of HCC cutaneous metastasis, the general appearance of such lesions resembles pyogenic granulomas, granuloma teleangiectaticum, or reddish-blue nodules. However, different from those described in the literature, a good prognosis was observed in this patient owing to the absence of intra-hepatic recurrence.