Abstract
Granular cell tumor is a rare benign neoplasm of the skin that accounts for 0.5% of all soft-tissue tumors. Granular cell tumor can affect both sexes and in any age, although it is most common in females. The common locations are the head and neck, the tongue is affected in 25% of cases but any internal organs can be affected such as soft tissue, bronchus, stomach, rectum, anus, biliary ducts. Here, we report a 58-year-old female patient who presented with a 4-year history of a slowly growing mass, with a dimension of 5 × 4 cm on her left waist, diagnosed as a Granular cell tumor at histopathological examination.
Highlights
Granular cell tumor (GCT), known as Abrikossoff tumor, is an uncommon benign neoplasm thought to be neural in origin and derived from Schwann cells.[1]
The excised specimen consists of skin measure 6x3x2.7 cm with brown colour nodular area in the centre with white dot like areas in the surface. The histopathological examination with HE stain shows nests of tumor cells separated by fibrous connective tissue in the dermis and subcutis
GCT is a benign tumor originating from Schwann cells
Summary
Granular cell tumor (GCT), known as Abrikossoff tumor, is an uncommon benign neoplasm thought to be neural in origin and derived from Schwann cells.[1] GCTs are more common in females than males.[2] It typically presents as a slow-growing, solitary, and painless nodular lesion located at the cutaneous and subcutaneous level (43%), on the tongue (23%), or any other part of the body.[3] Granular cell tumours have been reported in all age groups ranging from 11 months to 85 years, most cases generally occur between the 4th and 6th decades of life.[4]
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