Abstract

IntroductionFungal infections in the immunocompromised host are fairly common. Of the mycoses, Fusarium species are an emerging threat. Fusarium infections have been reported in solid organ transplants, with three reports of the infection in patients who had received renal transplants. To the best of our knowledge, this is the first case of an isolated cutaneous lesion as the only form of infection.Case presentationWe report the case of a 45-year-old South Indian man who presented with localized cutaneous Fusarium infection following a renal transplant.ConclusionIn an immunocompromised patient, even an innocuous lesion needs to be addressed with the initiation of prompt treatment.

Highlights

  • Fungal infections in the immunocompromised host are fairly common

  • Case presentation: We report the case of a 45-year-old South Indian man who presented with localized cutaneous Fusarium infection following a renal transplant

  • The Fusarium species most frequently involved in human infections are Fusarium solani, F. oxysporum and F. moniliforme

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Summary

Introduction

Fusarium species are common soil saprophytes and plant pathogens. Young and Meyers [1] first reported Fusarium infection in the late 1970s. Case report A 45-year-old South Indian man underwent a renal allograft transplant for end-stage renal disease. He was administered tacrolimus, mycophenolate and prednisolone as immunosuppressive therapy. On follow-up at six months, he complained of a small, painless nodule on his right calf. He had no fever, redness or pruritus. A biopsy sample was cultured for fungi on Sabouraud dextrose agar without cycloheximide and was incubated at 25°C in air for four days. It grew whitish-gray cottony colonies suggestive of Fusarium spp. The patient was successfully treated with surgical excision of the lesion followed by four weeks of oral voriconazole treatment

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