Abstract
Various systemic and even topical drugs were observed to induce acute or chronic pruritus. It is estimated that pruritus may account for about 5 % of all skin adverse reaction after drug intake. It could be localized or generalized. Frequently, the underlying mechanism of drug-induced pruritus is largely unknown. It may start with the first drug administration or may be delayed in time for several weeks or even months. Remarkably, this symptom may also resolve shortly after drug discontinuation or may persist even for several months or years after treatment withdrawal. The current review aims to give a detailed summary about drug-induced pruritus with a special emphasis on systematic grouping of the different forms of drug-induced pruritus and present a therapy of this side effect.
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