Abstract

Primary Angiosarcoma of the skin of the foot is very rare. Angiosarcoma is typically treated with resection and wide-field postoperative radiation therapy. Chemotherapy and radiation therapy have also been used. Regardless of the treatment, the risk of local and distant relapse remains high for this disease. We present a case of an elderly patient who developed cutaneous angiosarcoma of the foot. It posed as a diagnostic dilemma at presentation. Chronic lymphedema was a possible predisposing factor. Given his age, preexisting renal dysfunction, refusal of surgery, and preference not to receive chemotherapy, the patient was ultimately treated with definitive radiotherapy. We present this case because of its rare site, unique presentation and delay in diagnosis of the condition, and attainment of an excellent response to radiation at the time of follow-up. We also review the current literature on this topic.

Highlights

  • Angiosarcoma is a rare, malignant neoplasm comprising 1– 3% of adult soft tissue sarcomas [1,2,3,4]

  • The present study describes a case of cutaneous angiosarcoma of the foot in the setting of chronic lymphedema which was treated with definitive radiation alone

  • A rare case of cutaneous angiosarcoma of the foot has been described in this case report

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Summary

Introduction

Angiosarcoma is a rare, malignant neoplasm comprising 1– 3% of adult soft tissue sarcomas [1,2,3,4]. This is typically a tumor of older individuals with a median age of 70–75 years and a male predominance, having a predilection for the scalp and central area of the face. The neoplasm tends to invade tissue more widely than is clinically apparent and is prone to incomplete excision. The present study describes a case of cutaneous angiosarcoma of the foot in the setting of chronic lymphedema which was treated with definitive radiation alone. The patient was informed that data from the case would be submitted for publication and he provided the required consent

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