Abstract
Background Angiomyolipomas are tumors composed of adipose tissue, blood vessels and smooth muscle. Although renal angiomyolipomas are well known, cutaneous tumors have been described only recently. HMB-45 reactivity, reported for renal angiomyolipomas, has been suggested as a useful tool in differential diagnosis.Objective Two cases of cutaneous angiomyolipoma are described and investigated for HMB-45 reactivity.Methods Conventional histochemical and immunohistochemical methods were used.Results Immunohistochemical analysis showed no reactivity for HMB-45 antibody.Conclusion We conclude that, unlike renal angiomyolipomas, HMB-45 reactivity is not helpful in differentiating cutaneous angiomyolipomas.
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