Abstract
Een twaalf jaar oude, vrouwelijke, gesteriliseerde greyhound werd aangeboden met ulceratievenodulaire letsels, algemene zwakte en pijn. De hond werd op dat moment behandeld met prednisolonevoor een vermoedelijke diagnose van cervicale discus hernia. Op het microscopisch onderzoek van eenfi jnenaaldaspiratie-biopt van de nodulaire letsels werden protozoaire tachyzoïeten gezien. Het immunohistochemischonderzoek bevestigde de diagnose van Neospora caninum-infectie. Een behandeling metclindamycine en de stopzetting van een immunosuppressieve behandeling leidden tot volledig herstel. Ditartikel beschrijft het eerste geval van cutane neosporose in België.
Highlights
Neospora caninum is a protozoan of the phylum Apicomplexa first described in 1988 (Dubey et al, 1988)
This report documents the first case of cutaneous neosporosis in Belgium
Cutaneous neosporosis has been reported in eleven dogs which resided in the United States, France, Israel, Italy, Spain and the United Kingdom
Summary
Neospora caninum is a protozoan of the phylum Apicomplexa first described in 1988 (Dubey et al, 1988). A fine needle aspiration of the cutaneous nodule in the dorsal neck was performed, and revealed a mainly neutrophylic inflammation with multiple extracellular curvilinear tachyzoites with an apical nucleus (Figure 2). This nodule was surgically removed, fixed in 10 % buffered formalin solution and routinely processed for microscopic examination with hematoxylin and eosin stain (H&E). The owner noticed a marked improvement: the dog had a normal posture and gait. The physical examination was normal, and no pain reaction could be elicited Another two weeks later, the liver enzymes normalized, but the CK activity (213 U/liter) was still marginally elevated.
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