Abstract
IntroductionCustomised individually made (CIM) implants for total knee arthroplasty (TKA) were introduced about 10 years ago. These implants aim to reduce the risk of prosthesis-related issues resulting from anthropometric differences between different knees.The purpose of this study was to analyse the short-term clinical outcome and patient reported outcome measures (PROMs) of a specific CIM implant, the ORIGIN® knee replacement system (Symbios, Yverdon-les-Bains, Switzerland), which was introduced in 2018.Materials and methodsThis is a prospective cohort study of patients undergoing primary posterior-stabilised (PS) CIM TKA using the specific ORIGIN® knee replacement system, (Symbios, Yverdon-les-Bains, Switzerland). TKAs were performed from February 2019 to October 2020. Data was collected preoperatively and postoperatively at 4 and 12 months. Outcome measures included the objective part of the Knee Society Score (KSS) with the range of motion (ROM) and the following PROMs: the Knee injury and Osteoarthritis Outcome Score (KOOS), the Forgotten Joint Score (FJS-12), the EuroQol, five dimensions, three levels (EQ-5D-3L) with the EuroQol visual analogue scale (EQ-VAS) and patient satisfaction. Differences in pre- to preoperative data were assessed with paired sample t tests. A p value < 0.05 was considered significant.ResultsTwenty-five CIM TKA (20 patients, 8 female) were included. The mean age at surgery was 66 years (SD, 6.9). At 4 and 12 months, significant improvements in the KSS (p < 0.001), the ROM (p < 0.001), all KOOS subscales (p < 0.001), the FJS (p < 0.001) and the EQ-5D-3L (p < 0.026) were found. Satisfaction rate was 91% and 88% at 4 and 12 months, respectively. Intraoperative complications did not occur and no revision surgeries were undertaken.ConclusionsThe present study demonstrated significant improvements in the KSS and specific PROMs 1 year after CIM TKA. This study suggests that CIM TKA is a safe and suitable option, which can yield good clinical outcome and PROMs at least during short-term follow-up.
Highlights
Customised individually made (CIM) implants for total knee arthroplasty (TKA) were introduced about 10 years ago
Hirschmann et al [8,9,10] have shown a high variability of the medial femoral mechanical angle and the medial tibial mechanical angle within the three classical limb phenotypes in a non-osteoarthritic Caucasian population
The CIM TKAs were performed between February 2019 and October 2020 in a private hospital by one experienced board-certified surgeon specialised in knee surgery (MPA)
Summary
Customised individually made (CIM) implants for total knee arthroplasty (TKA) were introduced about 10 years ago. The purpose of this study was to analyse the short-term clinical outcome and patient reported outcome measures (PROMs) of a specific CIM implant, the ORIGIN® knee replacement system (Symbios, Yverdon-les-Bains, Switzerland), which was introduced in 2018. Conclusions The present study demonstrated significant improvements in the KSS and specific PROMs 1 year after CIM TKA. Aseptic loosening, instability and patellofemoral disorders, which are responsible for about 40% of all revision causes, are known to be affected by TKA component size or positioning [6, 7] These issues might theoretically be reduced by a more individualised, patient-specific approach. Several studies have demonstrated that among different ethnic groups different mediolateral-to-anteroposterior ratio of tibia and femur exist [11,12,13]
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