Abstract

Objectives: To determine the current status of skin infections causing bacteria and their pattern of resistance to widely used antibiotics among the physician referred patients in district Peshawar, Pakistan. Materials and methods: A cross-sectional study of 164 pus samples from diseased patients, referred by physicians was done for a period from February 2020 to January 2021 at Department of Microbiology, Complex medical laboratory and Research center, Peshawar, Pakistan. Results: The bacterial growth were obtained in 88 pus samples. Among these isolated bacterial species Escherichia coli was the most prevalent pathogen, present in (46%), Staphylococcus aureus (39%), Proteus species (11%), Klebseilla species (2%) and Pseudomonas aerugenosa (2%), respectively. Among the tested antibiotics resistance wise E.coli was highly resistance to Ampicillin (92.5%), S. Aureus to Levofloxacin (91.1%), Proteus spp .to Doxycycline (90%), Klebsiella spp. to Meropenem (100%), Amoxicillin (100%) and P. aeruginosato Aztreonam (100%), Doxycycline (100%), respectively.Sensitivity wise E.coli was highly sensitive to Amikacin (90%), S. aureus to Meropenem (91.1%) and Doxycycline (91.1%),Proteus spp. to Meropenem (100%), Klebsiella spp. to Ciprofloxacin (100%), Cefotaxime (100%), Aztreonam (100%) and Doxycycline (100%), P. aeruginosa to Amikacin (100%), Meropenem(100%), Ciprofloxacin (100%), Gentamicin (100%), Cefotaxime (100%), Ceftriaxone (100%), Ampicillin (100%) and Cefotaxime (100%), respectively. Conclusion: The most prevalent skin infections causing bacteria was E.coli, followed by S. aureus, Proteus spp., Klebseilla spp. and P. aerugenosa, respectively. The antibiogram provides adequate knowledge of effective therapeutic agents for the treatment strategies of skin infections.

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