Abstract
Regional ileitis is a low-grade granulomatous disease of the small bowel, usually involving 8 to 16 inches of the terminal loop of the ileum, just proximal to the ileocecal valve. The disease is nonspecific in nature; the etiology is unknown. The onset of the disease usually begins in youth. The average age of a person at which this occurs is 27 years. The clinical picture is dominated by diarrhea, abdominal pain, loss of weight, a moderate secondary anemia, and the formation of a tender mass in the right lower quadrant of the abdomen. Fistula formation is characteristic of the disease, with the fistulas appearing usually on the abdominal wall in the scar of a previous operation or as perirectal abscesses and fistulas. The disease is one of low-grade intensity, pursuing a course covering many years. The complications consist of hemorrhage, rarely perforation, but not infrequently of bouts of intestinal obstruction.
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