Abstract
Vaccination of adult cattle with 1/25th of the standard dose of strain 19 reduced the number of cattle removed from 110 herds in one year by 85% in 85 dairy herds and by 90% in 25 beef herds. This dose also minimized the effects of false positive reactions to serological tests. Complement fixation was found to be superior to other tests for diagnosing infection in vaccinated cattle.
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