Current status and progress of preoperative diagnosis of mediastinal lymph node metastasis of non-small cell lung cancer

Abstract

In recent years, the incidence of lung cancer, high mortality, become one of the main diseases that threaten human health and life. Preoperative staging of non-small cell lung cancer, especially mediastinal lymph node staging is the key to determine whether surgery and judge tne prognosis of patients. Therefore, how to achieve accurate staging of mediastinal lymph node before surgery is a clinical problem to be solved urgently. The traditional methods of preoperative staging of mediastinal lymph nodes include imaging, minimally invasive biopsy and surgery. In recent years, the development of relevant serum tumor markers, serum miRNAs and clinical prediction models provide some new references for the preoperative diagnosis and assessment of mediastinal lymph node metastasis. This paper reviews the methods of preoperative diagnosis of mediastinal lymph node metastasis of non-small cell lung cancer in recent years, and summarizes and analyzes the advantages and disadvantages of various methods. Key words: Carcinoma, non-small-cell lung; Mediastinum; Lymphatic metastasis; Diagnosis