Abstract
A comprehensive review of prophylactic use of perioperative antibiotics in trauma from the 1970s to the present was performed. Evidence based guidelines were used to analyze the data from the past 32 years and define standards of care in the field. Recommendations and suggestions are provided to offer guidelines for prophylactic antibiotic use in trauma. Highlighted topics include general trauma surgery, with focus placed on abdominal and thoracic surgery in trauma, and non-trauma surgery, including subspecialties, for comparison.
Highlights
Management of surgical site infections has remained an important topic over the years, and use of prophylactic perioperative antibiotics continues to ignite controversy
While there is no doubt that antisepsis has changed the face of surgery, there exists a wide spectrum of beliefs on duration and use of perioperative antibiotics
More and more literature has emerged in an attempt to provide guidelines for prophylactic antibiotic use in trauma patients undergoing surgery
Summary
Management of surgical site infections has remained an important topic over the years, and use of prophylactic perioperative antibiotics continues to ignite controversy. Despite the decreased morbidity and mortality ascribed to antisepsis, there are complications associated with overuse. The history of this topic dates back more than thirty years and the need for guidelines for antibiotic use is more necessary today than ever before. LEJLA HADZIKADIC: CURRENT PROPHYLACTIC PERIOPERATIVE ANTIBIOTIC GUIDELINES IN TRAUMA: A REVIEW OF THE LITERATURE AND OUTCOME DATA. The studies cited in support of the current recommendations have been selected using a Medline search since. Most citations supporting the current recommendations are prospective, randomized studies with retrospective data used in cases where prospective data is unavailable
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