Abstract

Objective: Effective management of patients diagnosed with ototoxicity is needed to reduce hearing and balance damage which affects communication and life quality. Despite widespread recommendations to monitor and manage ototoxicity in an early and effective manner, there is limited evidence to support the actual implementation of these recommendations for affected patient groups in healthcare services across the UK with limited publications available. In this study, an online questionnaire analysed the current practice of ototoxicity management and patient pathways across the UK once the diagnosis of ototoxicity was confirmed, targeting Audiologists, ENTs/AVPs and GPs. Design: Qualitative Survey Study. Study sample: A randomised sample of hearing services in the UK, including audiology departments; GP practices and local health settings were targeted with a total of 134 completed surveys. Results: About 72% reported the absence of ototoxicity management protocols within their centre. Results depicted great inconsistency and variation across the UK in ototoxicity management services provided, treatment modification, monitoring and referral pathways. Conclusion: Developing and advocating national guidelines are intended not only to inform clinical decision making but to provide minimum standards of care in ototoxicity management and offer greater awareness and education to improve patients’ quality of life.

Highlights

  • Drug ototoxicity is defined as a temporary or permanent druginduced ear dysfunction resulting in sensorineural hearing loss, tinnitus and/or disequilibrium

  • Results are reported as adjusted relative frequencies (ARF), or relative frequency (RF) of respondents by choice or absolute frequencies (AF)

  • ARF is the percentage of respondents who selected a given option, from the total number of respondents to the given question

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Summary

Introduction

Drug ototoxicity is defined as a temporary or permanent druginduced ear dysfunction resulting in sensorineural hearing loss, tinnitus and/or disequilibrium. Ototoxicity may seem a small price to pay for curing malignancies or severe infections, patients may perceive a hearing loss as a major effect on daily functioning and quality of life (Theunissen et al 2014). Hearing loss at speech frequencies up to 4 kHz may result in a deterioration of speech intelligibility. Hearing loss at higher frequencies (44 kHz) might have an adverse effect on the recognition and appreciation of sounds perceived in nature and music (birds, instruments, melodies) (Theunissen et al 2014). Ototoxic medications can lead to serious communication, educational, social and psychological difficulties significantly affecting the patient’s quality of life (WHO 1997)

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