Current possibilities in the prevention and therapy of ovarian hyperstimulation syndrome.

Abstract

To present current possibilities of the prevention and therapy of ovarian hyperstimulation syndrome (OHSS). Literature and guidelines were researched. From the view of safety and prevention of OHSS, antagonistic protocol is suitable. Patients with syndrome of polycystic ovaries benefit from the use of metformin or letrozole that can be sufficient to induce ovulation. As atreatment of imminent OHSS, it is recommended to administer 0.5 mg of cabergoline per os daily as well as low molecular weight heparin subcutaneously in prophylactic dose and to maintain sufficient fluid intake. Diuretics are strongly discouraged to use. To maintain intravascular volume, drained ascites can be reintroduced. We present areview of current literature and recommendations.