Current Perspectives on Extensive Applications of Nanocochleates-based Drug Delivery

Abstract

Abstract: Enhancing therapeutic efficacy stands as a pivotal concern across various medical conditions. Traditional therapeutic approaches have encountered limitations in addressing numerous issues. Over the recent years, the integration of nanotechnology has successfully overcome these obstacles, ushering in a new era of advanced treatment modalities. One notable stride has been the utilization of lipid-based nanocarriers, which have demonstrated substantial improvements in therapeutic outcomes. Among these innovative drug delivery systems (lipid-based), nanocochleates have emerged as the focal point for augmenting therapeutic potential and enabling targeted actions. Originally employed for vaccines, genes, and fungal infections, nanocochleates have evolved to address significant life-threatening diseases where conventional therapies fall short. The distinctive capability of nanocochleates lies in their ability to deliver drugs with enhanced precision in comparison with supplementary lipid-based systems, making them a promising novel carrier for improved efficacy. This piece of writing delves into the fundamentals of nanocochleates, exploring their safety and stability aspects, recent trends, and diverse applications. Notably, nanocochleates have shown promise in managing conditions such as diabetes mellitus, malaria, leishmaniasis, cancer, viral infections, and osteoporosis. By elucidating the unique attributes and potential of nanocochleates, this review aims to contribute valuable insights into their role as a cutting- edge drug delivery system across a spectrum of critical medical scenarios